Landow is also the founder and current webmaster of The Victorian Web, The Contemporary, Postcolonial, & Postimperial Literature in English web, and The Cyberspace, Hypertext, & Critical Theory web.
Professor Landow has published extensively on the Pre-Raphaelite Brotherhood, specifically the life and works of William Holman Hunt and John Ruskin. Furthermore, Landow's articles and books are of some importance to studies on the effects of digital technology on language. Landow discusses the effects of electronic media on literature, creating a plausible link with critics such as Jacques Derrida, Roland Barthes, Gilles Deleuze, Paul de Man, and Michel Foucault, among others. This places him in a slightly different position on issues such as "the end of books" through the prophetic and "futurologic" view often taken by critics regarding new media and literature.
Landow is a well-known author, researcher and one of the most important thinkers concerning Hypermedia and Hypertext in academia. His most important works highlight the epistemological modifications which result from the migration between systems of "closed" authorial publication (such as books), to the "open" systems, such as the hypertext and hypermedia.